Tough vines, poison ivy, and woody brush can quickly overwhelm fences, paths, and property edges, so many homeowners turn to specialized brush killers for fast, lasting control. From BioAdvanced Brush Killer Plus in several convenient formats to targeted options like Ortho GroundClear, Fertilome Brush Killer Stump Killer, BioAdvanced Extended Control, and Roundup Poison Ivy & Tough Brush Killer, each product tackles stubborn growth differently—and choosing the right one depends on a few often-overlooked factors.
| BioAdvanced Brush Killer Plus Ready-to-Use Weed Spray |
| Best For Small Jobs | Formulation Type: Ready-to-use sprayer (pre-mixed liquid) | Primary Target Weeds: Poison ivy, poison oak, blackberry, plus 75+ other weeds | Active Ingredient / Mode: Triclopyr-based brush killer (targets roots and vines) | VIEW LATEST PRICE | Read Our Analysis |
| BioAdvanced Brush Killer Plus 32 oz Concentrate |
| Most Versatile Concentrate | Formulation Type: Concentrate (mix with water; can be used full-strength on stumps) | Primary Target Weeds: Poison ivy, poison oak, kudzu, blackberry, plus 75+ weeds | Active Ingredient / Mode: 8.8% Triclopyr, triethylamine salt; systemic herbicide | VIEW LATEST PRICE | Read Our Analysis |
| BioAdvanced Brush Killer Plus Ready-to-Spray 32 oz |
| Hose-End Convenience Pick | Formulation Type: Ready-to-spray hose-end liquid | Primary Target Weeds: Poison ivy, poison oak, blackberry, kudzu, plus 75+ weeds | Active Ingredient / Mode: 8.8% Triclopyr, triethylamine salt; systemic brush killer | VIEW LATEST PRICE | Read Our Analysis |
| Ortho GroundClear Poison Ivy & Brush Killer Concentrate |
| High-Capacity Concentrate | Formulation Type: Concentrate (makes up to 8 gallons) | Primary Target Weeds: Poison ivy, poison oak, kudzu, wild blackberry, 60+ weeds/brush | Active Ingredient / Mode: Systemic herbicide absorbed through leaves (active not listed in summary) | VIEW LATEST PRICE | Read Our Analysis |
| Fertilome (11485) Brush Killer Stump Killer (32 oz) |
| Best For Stumps | Formulation Type: Concentrate (undiluted for stumps; diluted for brush) | Primary Target Weeds: Stumps and woody plants (vines, brush/woody weeds) | Active Ingredient / Mode: Brush/stump killer herbicide (active not listed in summary) | VIEW LATEST PRICE | Read Our Analysis |
| BioAdvanced Extended Control Brush Killer Spray Ready-to-Use 1 Gallon |
| Long-Term Control | Formulation Type: Ready-to-use trigger/sprayer (pre-mixed liquid) | Primary Target Weeds: Poison ivy, poison oak, blackberry, kudzu, English ivy, bamboo, other tough brush | Active Ingredient / Mode: 0.8% Triclopyr, triethylamine salt; extended-control systemic | VIEW LATEST PRICE | Read Our Analysis |
| Roundup Poison Ivy & Tough Brush Killer 1-Gallon |
| Fastest Results | Formulation Type: Ready-to-use with Comfort Wand (pre-mixed liquid) | Primary Target Weeds: Poison ivy, poison oak, poison sumac, wild blackberry, kudzu, tough weeds/brush | Active Ingredient / Mode: Brush/weed herbicide blend for woody and viney weeds (actives not listed in summary) | VIEW LATEST PRICE | Read Our Analysis |
More Details on Our Top Picks
BioAdvanced Brush Killer Plus Ready-to-Use Weed Spray
Should you be battling poison ivy, woody vines, or stubborn brush that keeps coming back, BioAdvanced Brush Killer Plus Ready-to-Use Weed Spray is built for you, providing triclopyr straight to the roots through an easy 1-gallon sprayer so you can tackle over 75 tough weed types without mixing, then let the rainproof formula go to work over the next few weeks. You’ll target poison ivy, poison oak, blackberry, and other woody invaders while they’re actively growing, helping stop regrowth from the roots up. Once it dries in about four hours, rain won’t wash away your work.
- Formulation Type:Ready-to-use sprayer (pre-mixed liquid)
- Primary Target Weeds:Poison ivy, poison oak, blackberry, plus 75+ other weeds
- Active Ingredient / Mode:Triclopyr-based brush killer (targets roots and vines)
- Rainproof Time:Rainproof in 4 hours
- Visible Results Time:1–6 weeks
- Typical Use Areas:Around homes and similar non-lawn areas with actively growing brush
- Additional Feature:Built-in 1-gallon sprayer
- Additional Feature:No mixing required
- Additional Feature:Targets vine-type weeds
BioAdvanced Brush Killer Plus 32 oz Concentrate
Should you be battling stubborn brush like poison ivy, kudzu, or blackberry brambles around your home, cabin, or wooded property, BioAdvanced Brush Killer Plus, 32 oz Concentrate is a strong pick for tough, root-killing control. This triclopyr-based systemic formula moves through leaves and roots to wipe out over 75+ woody weeds, including poison oak. You’ll cover up to 4,000 square feet through mixing the concentrate as directed, or you can paint it full strength on fresh-cut stumps. It becomes rainproof in 4 hours, with visible results in 1–6 weeks, and earns a solid 4.1-star rating from thousands of users.
- Formulation Type:Concentrate (mix with water; can be used full-strength on stumps)
- Primary Target Weeds:Poison ivy, poison oak, kudzu, blackberry, plus 75+ weeds
- Active Ingredient / Mode:8.8% Triclopyr, triethylamine salt; systemic herbicide
- Rainproof Time:Rainproof in 4 hours
- Visible Results Time:1–6 weeks
- Typical Use Areas:Around homes, cabins, buildings, fences, walkways, trails, wooded areas
- Additional Feature:Treats up to 4,000 sq.ft.
- Additional Feature:Full-strength stump treatment
- Additional Feature:Around buildings and trails
BioAdvanced Brush Killer Plus Ready-to-Spray 32 oz
For dense tangles of poison ivy, oak, blackberry, and kudzu that have taken over fences, trails, or wooded edges, BioAdvanced Brush Killer Plus Ready-to-Spray (32 oz) gives you a powerful, homeowner-friendly way to reclaim up to 4,000 square feet without mixing or special equipment. You just hook it to a hose, aim, and saturate actively growing brush. The 8.8% triclopyr formula targets more than 75 hard-to-kill woody weeds and vines while becoming rainfast in 4 hours. Expect visible decline in 1–6 weeks. Strong reviews (4.1/5 from thousands of ratings) back its reliability.
- Formulation Type:Ready-to-spray hose-end liquid
- Primary Target Weeds:Poison ivy, poison oak, blackberry, kudzu, plus 75+ weeds
- Active Ingredient / Mode:8.8% Triclopyr, triethylamine salt; systemic brush killer
- Rainproof Time:Rainproof in 4 hours
- Visible Results Time:1–6 weeks
- Typical Use Areas:Yards and non-lawn areas with brush/weed infestations up to 4,000 sq ft
- Additional Feature:Hose-end ready-to-spray
- Additional Feature:Treats up to 4,000 sq.ft.
- Additional Feature:Lightweight 2.13-pound bottle
Ortho GroundClear Poison Ivy & Brush Killer Concentrate
You’ll apply it only to leafed-out, actively growing weeds in non-garden areas, and it becomes rainproof in 2 hours. Because it’s a concentrate, you must mix it according to the label—never spray straight from the bottle.
- Formulation Type:Concentrate (makes up to 8 gallons)
- Primary Target Weeds:Poison ivy, poison oak, kudzu, wild blackberry, 60+ weeds/brush
- Active Ingredient / Mode:Systemic herbicide absorbed through leaves (active not listed in summary)
- Rainproof Time:Rainproof in 2 hours
- Visible Results Time:Wilting/yellowing in 2–6 weeks
- Typical Use Areas:Non-garden areas around homes, cabins, buildings, fences, trails
- Additional Feature:Makes 8 gallons
- Additional Feature:Rainproof in 2 hours
- Additional Feature:Over 60 weed species
Fertilome (11485) Brush Killer Stump Killer (32 oz)
Homeowners battling stubborn woody vines, invasive shrubs, or freshly cut stumps will appreciate how Fertilome (11485) Brush Killer Stump Killer streamlines tough cleanup. This 32 oz concentrate contains Triclopyr 8.8%, a potent active ingredient that tackles unwanted vegetation effectively. For stump treatment, you’ll apply the undiluted formula directly to freshly cut surfaces within 45 minutes—timing’s essential for maximum penetration. For leafy plants, mix 8 oz concentrate with one gallon of water and spray thoroughly. Results typically appear within one to six weeks, though patience pays off with complete root system elimination. It’s trusted by homeowners nationwide for conquering elm, sumac, poison ivy, and numerous broadleaf weeds around properties.
- Formulation Type:Concentrate (undiluted for stumps; diluted for brush)
- Primary Target Weeds:Stumps and woody plants (vines, brush/woody weeds)
- Active Ingredient / Mode:Brush/stump killer herbicide (active not listed in summary)
- Rainproof Time:Not specified (standard brush/stump killer; avoid rain during fresh application)
- Visible Results Time:Not specified (works over time on stumps/woody plants)
- Typical Use Areas:On stumps and woody plants/vines in landscape or non-crop areas
- Additional Feature:Undiluted stump brushing
- Additional Feature:Fresh-cut stump window
- Additional Feature:Concentrate leaf spraying
BioAdvanced Extended Control Brush Killer Spray Ready-to-Use 1 Gallon
Tough-brush battles call for a ready-to-use, long-lasting solution, and BioAdvanced Extended Control Brush Killer Spray fits when you want to kill woody weeds down to the root and keep them from coming back for up to 12 months. With 0.8% triclopyr triethylamine salt, it targets stubborn invaders like poison ivy, oak, blackberry, kudzu, English ivy, and even bamboo. The 1-gallon jug covers up to 500 square feet and turns rainproof in 4 hours, so your work doesn’t wash away. You’ll typically see wilting or yellowing within 1–28 days, confirming it’s working underground.
- Formulation Type:Ready-to-use trigger/sprayer (pre-mixed liquid)
- Primary Target Weeds:Poison ivy, poison oak, blackberry, kudzu, English ivy, bamboo, other tough brush
- Active Ingredient / Mode:0.8% Triclopyr, triethylamine salt; extended-control systemic
- Rainproof Time:Rainproof in 4 hours
- Visible Results Time:Wilting/yellowing in 1–28 days
- Typical Use Areas:Around property where long-term brush control (up to 12 months) is desired
- Additional Feature:Up to 12-month control
- Additional Feature:Covers 500 square feet
- Additional Feature:Extended control formula
Roundup Poison Ivy & Tough Brush Killer 1-Gallon
For eradicating poison ivy, poison oak, poison sumac, and other woody invaders creeping along fences, trails, and tree lines, Roundup Poison Ivy & Tough Brush Killer, 1-gallon with its reusable Comfort Wand gives you targeted control without constant bending or awkward sprayers. Its exclusive formula kills tough weeds like wild blackberry and kudzu to the root and turns foliage yellow or brown within hours. It’s rainproof in as fast as 30 minutes, so a passing shower won’t waste your work. You can treat residential fields, paths, and tree lines, then plant again 1–30 days later as directed.
- Formulation Type:Ready-to-use with Comfort Wand (pre-mixed liquid)
- Primary Target Weeds:Poison ivy, poison oak, poison sumac, wild blackberry, kudzu, tough weeds/brush
- Active Ingredient / Mode:Brush/weed herbicide blend for woody and viney weeds (actives not listed in summary)
- Rainproof Time:Rainproof in as fast as 30 minutes
- Visible Results Time:Visible results in hours
- Typical Use Areas:Residential fields and trails, around trees/shrubs, homes, cabins, fences, foundations, vines on poles or mature trees
- Additional Feature:Reusable Comfort Wand
- Additional Feature:Results in mere hours
- Additional Feature:Planting allowed after treatment
Factors to Consider When Choosing a Brush Killer
Choosing the right brush killer starts with matching its target weed range and active ingredient strength to the specific vines, saplings, and tough weeds on the property. Buyers also benefit from comparing residual control duration, as well as the application method and coverage that best fit their equipment and acreage. It is equally crucial to highlight the product’s rainfast time and speed of visible results, especially in areas with unpredictable weather.
Target Weed Spectrum
Shoppers should initially match the label to their environment, looking for products that specifically list the problem species, especially at the time of handling tough customers like poison oak or invasive vines. Some formulations control more than 75+ weed and brush species, while others are customized to a narrower set of plants. Because many brush killers work best during the weeds’ active growth phase, choosing an appropriate range also guides application timing.
Root-killing, systemic options are especially beneficial where woody stems and deep rhizomes threaten persistent regrowth.
Active Ingredient Strength
Strength, however, is not the only efficiency metric. Application rate and coverage per gallon matter just as much, since some lower-percentage products still treat large areas effectively at the time of application correctly. Matching concentration to weed maturity and growth stage helps avoid both underkill and unnecessary overkill.
Residual Control Duration
How long a brush killer keeps working after it dries can be just as important as how fast it burns down existing growth, since residual control duration determines how long roots, shoots, and new seedlings are suppressed before weeds return. Premium brush killers utilize specific active ingredients and formulations to extend protection against tough brush like poison ivy and poison oak for up to 12 months. Products containing glyphosate combined with imazapic deliver sustained suppression by targeting both existing vegetation and preventing new germination.
Application timing matters greatly—treating actively growing weeds maximizes the herbicide’s effectiveness and residual lifespan. Additionally, rainproof protection developing within hours guarantees continued potency after rainfall, maintaining consistent weed control throughout the season without frequent reapplication, ultimately reducing labor costs and maintenance demands.
Application Method & Coverage
Beyond how long a product lingers in the soil, the application method and coverage determine whether a brush killer fits a small yard project or a larger overgrown area. Ready-to-use sprays offer immediate convenience, eliminating mixing steps and often featuring built-in applicators for precise targeting.
Concentrate formulations provide greater coverage area efficiency, though they demand preparation time. Coverage capacity ranges dramatically—some products treat up to 4,000 square feet while others manage only 500. Rainproof protection within hours allows flexible scheduling despite unpredictable weather. For homeowners prioritizing ease, ready-to-spray options with ergonomic wands reduce hand fatigue during extended application sessions. Conversely, those managing expansive areas benefit from concentrates’ superior square-footage efficiency, justifying the extra preparation effort for thorough weed management across larger properties.
Rainfast Time & Speed
Upon evaluating brush killers, rainfast time and speed of results are critical for planning effective treatments in real-world weather conditions. Rainfast time is the window needed after application before rain will no longer wash the product off, and it varies widely according to formulation.
Some modern brush killers become rainproof in as little as 30 minutes, offering flexibility at times showers are unpredictable. Others might require up to 4 hours before they are fully rainfast, which matters at times rain is in the forecast soon after spraying. Visible results also differ: certain fast-acting formulas show injury within hours, while systemic products could take several days to weeks to reveal full dieback. In variable climates, choosing shorter rainfast times reduces the risk of wasted applications.
