5 Best Ortho Weed Killers for 2026

You can rely on five solid Ortho products for common yard weeds in 2026. They cover tough brush, crabgrass, broadleaf weeds, and spot treatments. Choices include ready-to-use sprays, concentrates, and a pump sprayer for larger jobs. Timing, turf safety, and applicator type guide effective use.

Our Top Ortho Weed Killer Picks

Ortho Brush-B-Gon Poison Ivy Oak & Brush Killer – Quart 0432760Best for Tough BrushProduct Name: Ortho Brush-B-Gon Poison Ivy Oak & Brush Killer – QuartTarget — Weeds/Brush: Tough brush and weeds (poison ivy, poison oak, kudzu, blackberries)Formulation Type: Concentrate (mix before use)VIEW LATEST PRICERead Our Analysis
Ortho WeedClear Lawn Weed Killer Ready-to-Use (1 gal) Ortho WeedClear Lawn Weed Killer Ready-to-Use, Refill, Kills Crabgrass, Dandelion Easy Spot TreatmentProduct Name: Ortho WeedClear Lawn Weed Killer Ready-to-Use Refill (1 gal)Target — Weeds/Brush: Common lawn weeds (crabgrass, dandelion, clover)Formulation Type: Ready-to-use (refill bottle for Comfort Wand)VIEW LATEST PRICERead Our Analysis
Ortho GroundClear Concentrate Weed & Grass Killer (32oz) Ortho GroundClear Weed and Grass Killer2 Concentrate, Kills Dandelions, Chickweed, Organic-Friendly ConcentrateProduct Name: Ortho GroundClear Weed and Grass Killer2 Concentrate (32 fl. oz.)Target — Weeds/Brush: Weeds and unwanted grasses (dandelions, crabgrass, moss, oxalis, etc.)Formulation Type: Concentrate (dilute per label; tank sprayer)VIEW LATEST PRICERead Our Analysis
Roundup Weed & Grass Killer 1.33 gal with Sprayer Roundup Weed and Grass Killer₄ with Pump 'N Go 2 Heavy-Duty CoverageProduct Name: Roundup Weed & Grass Killer with Pump ’N Go 2 Sprayer (1.33 gal)Target — Weeds/Brush: Tough weeds and grasses (dandelion, crabgrass, poison ivy, clover, spotted spurge)Formulation Type: Ready-to-use spray (pump sprayer included)VIEW LATEST PRICERead Our Analysis
Ortho Weed B Gon Plus Crabgrass Control Ready-To-Use Comfort Wand 1 gallon Ortho Weed B Gon Plus Crabgrass Control Ready-To-Use Comfort Wand, Best Lawn ProtectorProduct Name: Ortho Weed B Gon Plus Crabgrass Control Ready-To-Use Comfort Wand (1 gal)Target — Weeds/Brush: Lawn weeds including crabgrass, dandelions and 200+ listed weedsFormulation Type: Ready-to-use (trigger/Comfort Wand applicator)VIEW LATEST PRICERead Our Analysis

More Details on Our Top Picks

  1. Ortho Brush-B-Gon Poison Ivy Oak & Brush Killer – Quart 0432760

    Best for Tough Brush

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    Should you’re handling with dense, stubborn brush and want a product that handles the worst of it, Ortho Brush-B-Gon Poison Ivy Oak & Brush Killer quart fits the bill. You’ll find a 32 oz concentrate labeled Ortho MAX Poison Ivy Tough Brush Killer that mixes for use. You can treat over 60 types of tough brush and weeds, including poison ivy, poison oak, kudzu, and wild blackberries. You’ll appreciate the focused formula that targets brushy weeds without vague promises. Keep in mind that this model 0432760 isn’t sold on Catalina Island. You’ll mix carefully and apply where those species trouble you most.

    • Product Name:Ortho Brush-B-Gon Poison Ivy Oak & Brush Killer – Quart
    • Target — Weeds/Brush:Tough brush and weeds (poison ivy, poison oak, kudzu, blackberries)
    • Formulation Type:Concentrate (mix before use)
    • Volume/Size:32 oz (1 quart)
    • Application Method:Mix concentrate and apply (sprayer)
    • Lawn/Plant Use Guidance:For control of brush/woody weeds (not lawn-use focused)
    • Additional Feature:Concentrate formulation for mixing
    • Additional Feature:Kills tough brush species
    • Additional Feature:Not for Catalina Island
  2. Ortho WeedClear Lawn Weed Killer Ready-to-Use (1 gal)

    Ortho WeedClear Lawn Weed Killer Ready-to-Use, Refill, Kills Crabgrass, Dandelion

    Easy Spot Treatment

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    Should you want a simple, no-fuss way to zap common lawn weeds without kneeling or mixing chemicals, this one-gallon Ortho WeedClear ready-to-use refill is made for you. You’ll attach your battery-powered Ortho Comfort Wand and spray a continuous stream for easy spot treatment. It kills crabgrass, dandelion, clover, and many other common weeds with fast action from a single application. You won’t harm your Bermudagrass, Buffalograss, Fescues, Kentucky Bluegrass, Ryegrass, or Zoysiagrass provided you follow the label directions. You’ll appreciate the refill size for larger yards and the simple handling that keeps yard work quick and tidy.

    • Product Name:Ortho WeedClear Lawn Weed Killer Ready-to-Use Refill (1 gal)
    • Target — Weeds/Brush:Common lawn weeds (crabgrass, dandelion, clover)
    • Formulation Type:Ready-to-use (refill bottle for Comfort Wand)
    • Volume/Size:1 gallon (128 fl. oz.)
    • Application Method:Attach to battery-powered Comfort Wand; continuous stream spot treatment
    • Lawn/Plant Use Guidance:Safe for listed lawn grasses when used as directed
    • Additional Feature:Ready-to-use refill bottle
    • Additional Feature:Battery-powered Comfort Wand compatible
    • Additional Feature:Continuous stream spot-treatment
  3. Ortho GroundClear Concentrate Weed & Grass Killer (32oz)

    Ortho GroundClear Weed and Grass Killer2 Concentrate, Kills Dandelions, Chickweed,

    Organic-Friendly Concentrate

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    In case you want a fast, reliable way to zap weeds around driveways, patios, and scenery beds without touching your lawn, Ortho GroundClear Concentrate is a smart pick because it works on contact and shows results in as little as 15 minutes. You’ll mix the 32 oz concentrate with water in a tank sprayer and treat up to 600 sq ft. It targets dandelions, crabgrass, moss, and more. It’s rainproof after about two hours once dry. Don’t spray wanted plants and keep children and pets out until the spray dries. Repeat treatments might be needed.

    • Product Name:Ortho GroundClear Weed and Grass Killer2 Concentrate (32 fl. oz.)
    • Target — Weeds/Brush:Weeds and unwanted grasses (dandelions, crabgrass, moss, oxalis, etc.)
    • Formulation Type:Concentrate (dilute per label; tank sprayer)
    • Volume/Size:32 fl. oz.
    • Application Method:Dilute and apply with tank sprayer (spray on contact)
    • Lawn/Plant Use Guidance:Not for lawns or desirable grasses; for patios, walkways, beds
    • Additional Feature:Active: ammonium nonanoate
    • Additional Feature:OMRI listed (organic use)
    • Additional Feature:Treats up to 600 sq. ft.
  4. Roundup Weed & Grass Killer 1.33 gal with Sprayer

    Roundup Weed and Grass Killer₄ with Pump 'N Go 2

    Heavy-Duty Coverage

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    In case you want a no-fuss solution that kills tough weeds and grasses fast, the Roundup Weed & Grass Killer with Pump ‘N Go 2 Sprayer is a solid pick for busy homeowners and gardeners who need reliable results without mixing chemicals. You get 1.33 gallons ready to spray, with triclopyr, fluazifop-P-butyl, and diquat dibromide working together to kill weeds to the root. You’ll see results in hours and it’s rainproof in about 30 minutes. The Pump ’N Go sprayer gives up to 10 minutes continuous spray and an extendable wand for precise application around beds, paths, and fences.

    • Product Name:Roundup Weed & Grass Killer with Pump ’N Go 2 Sprayer (1.33 gal)
    • Target — Weeds/Brush:Tough weeds and grasses (dandelion, crabgrass, poison ivy, clover, spotted spurge)
    • Formulation Type:Ready-to-use spray (pump sprayer included)
    • Volume/Size:1.33 gallons (170 fl. oz.)
    • Application Method:Pump ’N Go 2 sprayer with extendable wand (spray)
    • Lawn/Plant Use Guidance:Use around beds, foundations, walkways; avoid contact until dry
    • Additional Feature:Pump ’N Go 2 sprayer
    • Additional Feature:Rainproof in ~30 minutes
    • Additional Feature:Multiple active ingredients
  5. Ortho Weed B Gon Plus Crabgrass Control Ready-To-Use Comfort Wand 1 gallon

    Ortho Weed B Gon Plus Crabgrass Control Ready-To-Use Comfort Wand,

    Best Lawn Protector

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    Provided you want a simple way to zap weeds without dragging out a spreader or mixing chemicals, the Ortho Weed B Gon Plus Crabgrass Control Ready-To-Use with Comfort Wand is built for you. You’ll like the 1 gallon trigger bottle because it fits your hand and lets you target problem spots. It kills 200 plus listed weeds, including crabgrass and dandelions, and starts to work within hours. You can treat roots with a gentle squeeze and not worry provided you follow directions. Reviews average 4.3 of 5, and manufacturer support is available in case you need help or warranty details.

    • Product Name:Ortho Weed B Gon Plus Crabgrass Control Ready-To-Use Comfort Wand (1 gal)
    • Target — Weeds/Brush:Lawn weeds including crabgrass, dandelions and 200+ listed weeds
    • Formulation Type:Ready-to-use (trigger/Comfort Wand applicator)
    • Volume/Size:1 gallon (140.8 fl. oz.)
    • Application Method:Built-in Comfort Wand trigger applicator for spot treatment
    • Lawn/Plant Use Guidance:Won’t harm lawns when used as directed; intended for lawn spot treatment
    • Additional Feature:Built-in Comfort Wand trigger
    • Additional Feature:Kills 200+ listed weeds
    • Additional Feature:Spot treatment with trigger applicator

Factors to Consider When Choosing Ortho Weed Killers

While you’re choosing an Ortho weed killer, consider about what weeds you need to control and whether the product is safe for your lawn grass. Check the active ingredients and concentration to match the target weeds and to know how much coverage and what application method you’ll need. That way you’ll pick a product that’s effective, gentle on your yard, and easy to use.

Target Weed Types

Start through figuring out exactly what kind of weeds you’re battling, because that choice will steer everything else and save you time and worry. Initially, check whether they’re broadleaf like dandelion, clover, plantain or grassy such as crabgrass and annual ryegrass. That tells you which herbicide family will work best. Next, notice whether plants are annuals that die each season or perennials that come back from roots. Perennials often need systemic products or repeat treatments. For woody brush like poison ivy, kudzu, or blackberries pick formulas labeled for brush control that move to roots. Also look at size and growth stage since many products hit small, actively growing weeds better than mature ones. To begin, read the label to confirm it names your exact species.

Lawn Safety Compatibility

Choosing an Ortho weed killer that’s safe for your lawn starts with reading the label and matching it to your grass type, because not every product treats weeds without hurting the turf you love. Check the label for phrases like “safe for use on” your grass species, such as Bermudagrass, Fescue, Kentucky bluegrass, Ryegrass, or Zoysiagrass. Also confirm whether the formula is for spot treatment or whole lawn use since concentrates and ready to use sprays behave differently. Pay attention to re entry and pet or children restrictions and follow the drying time before normal use. Don’t spray during heat stress, drought, or on newly sodded or overseeded lawns. Finally, follow pre emergent versus post emergent timing to protect your turf.

Active Ingredient Profile

You’ve already checked that a product won’t harm your grass, and now it helps to look closer at what’s actually inside the bottle. The active ingredient tells you how the herbicide works, whether it kills only tissue it touches or moves through the plant to the roots. Check which weeds it targets since some chemicals hit broadleaf weeds, others attack grasses, and a few do both. You’ll also want to notice concentration and formulation because they change how much you mix, how fast you see results, and how it handles in use. Some actives are nonselective and will kill desirable plants on contact, while selective ones spare certain turfgrasses when used correctly. Finally, consider environmental persistence and any restrictions that affect scheduling and safety.

Application Method Needed

While treating weeds, the way you apply the product matters as much as the formula inside the bottle, so consider comfort, control, and the size of the job before you pick an applicator. You’ll want ready-to-use trigger or wand applicators whenever you need precise spot treatment and don’t want to mix concentrates. For bigger patches choose pump or battery-powered continuous stream wands to cut down on bending and fatigue. Tank sprayers with adjustable nozzles work best whenever you dilute concentrates and need to control spray volume and droplet size. In windy or planted areas use foam or shielded applicators to limit drift and protect flowers and vegetables. Reflect on capacity and coverage rate so you won’t refill too often during the job.

Coverage And Concentration

Assuming you want your weed treatment to actually cover the ground you care about, start checking the product’s concentration and the label’s coverage numbers so you know what a bottle will do for your yard. You’ll want to compare concentrate strength and dilution rates, since a 32 fl oz concentrate mixed correctly can treat far more square feet than a ready-to-use spray. Look at stated coverage per container and match it to your lawn size to figure out bottles or refills. For spot jobs, ready-to-use applicators give precise placement, while concentrates with tank sprayers save money on large areas. Note whether coverage is listed for the diluted solution and follow those ratios. Also plan for multiple applications should tough weeds need repeat treatments.

Speed Of Visible Results

At the time you desire fast results, consider about how the product works and what conditions you’re operating in. You’ll notice contact herbicides often wilt or brown plants within minutes to a few hours, with full dieback in one to three days. In contrast, systemic products require time to move through the plant, so yellowing or stunting could show after days or weeks. Weather matters a lot. Warm sunny dry days speed activity, while cool cloudy or wet periods slow it down. Plant size and growth stage matter too. Small actively growing weeds respond faster than large woody or dormant plants, which can take weeks or need repeat treatments. Also weigh formulation and mode of action for quick symptom onset versus longer lasting control.

Environmental And Safety Notes

Because you’ll be using powerful chemicals around your home, consider safety for people, pets, and the environment before you spray. Read labels closely because they tell you when treated areas are safe to re-enter and when products become rainproof, often within 30 minutes to 2 hours. Don’t apply should rain be expected in that window to avoid runoff and poor results. Wear gloves, long sleeves, and eye protection whenever mixing or applying concentrates to lower exposure risks. Avoid spraying on windy days and keep droplets off desirable plants to prevent off-target damage. Rinse equipment thoroughly to stop residue transfer. Store concentrates locked in a ventilated place away from kids and pets, and dispose of empty containers and extras according to local hazardous-waste rules.

Gardening Editorial Team
Gardening Editorial Team

Founded to help gardeners grow healthy, thriving plants, our team of experienced horticulturists and gardening experts carefully researches and produces content grounded in practical knowledge and proven techniques.